Theme: Advancements in Global Pharma & Drug Research

Drug Discovery 2021

Renowned Speakers

Magnus S. Magnusson
Human Behavior Laboratory, University of Iceland
Iceland

Jams Otniel Rychard Rumahorbo
Bandung Institute of Technology, Indonesia
Indonesia

Zeeshan Ahmad
De Montfort University
UK

Francois-Xavier Frapaise
F.-X. Frapaise Consulting,
France

Oleg V Tcheremissine
Atrium Health,USA
USA

Edwin G Moore
University of Illinois, Urbana
USA

Drug Discovery 2021

Conference Series LLC Ltd is delighted to invite you to attend the 7th World Congress on Pharmaceutical Research & Drug Discovery, one of its remarkable Pharmaceutical conferences, to be held during December 16-17, 2021, Webinar with the theme "Exploring the recent trends and advances in the field of Drug Discovery research and innovations in the pharma" emphasizing on recent areas of more optimized research techniques like rational and computer aided drug designing for the Discovery, Designing and Development of new drugs than by traditional hit and trial method. This Drug Discovery 2021 Conference includes a wide range of Keynote presentations, Oral talks, and Poster presentations.

Conference Series LLC Ltd Organizes 2000+ Global Events Every Year across USA, Asia & Europe with support from 1000 more scientific societies and Publishes 600+ Open access journals which contains over 100000 eminent personalities, reputed scientists as organizing committee members and editorial board. The conference series website will provide you list and details about the conferences organize worldwide.

Why to attend???

The DRUG DISCOVERY 2021 anticipates participants, renowned speakers and eminent delegates across the globe to be attending the conference to share their valuable presentation and galvanize the scientific community. Scientific people from all over the globe focused on learning about emerging technologies about Drug Discovery and Advanced Drug Design Technology in the latest application. This is a best globalized opportunity to reach the largest assemblage of participants from the scientific community and research.

Conduct presentations, meet with current, potential scientists, distribute information and make a splash with new drug research developments, and receive name recognition at this event. Renowned speakers and therefore the most up-to-date techniques, developments, the most recent updates in Drug Discovery are hallmarks of this conference.

Who should attend and Whom You’ll Meet?

Directors/Senior Directors/Executive Directors and Vice Presidents/Senior Vice Presidents/Executive Vice Presidents and Heads/Leaders/Partners of
• CROs and CMOs
• Pharma Research Sites
• Pharma/Biotech and Medical Device industries
• Hospitals, Associations

Target Audience:
Our Organization would be privileged to welcome the:
• Noble laureates
• Pharmaceutical Researchers
• Pharmaceutical Industry Professionals (CEOs, MDs, Directors)
• Academicians (Professors, Deans, Directors)
• Pharmaceutical Associations and Societies
• Young Researchers and Students
• Post- Doctoral
• Graduates and Post Graduates in Pharmaceutics
• PhD in Pharmaceutical Sciences
• Software development companies
• Government healthcare departments, HTA’s and drug regulators
• Genomics and personalized medicine experts

Corona Virus Drug Discovery

The profoundly pathogenic Covids extreme intense respiratory condition Covid (SARS-CoV) and Middle East respiratory disorder Covid (MERS-CoV) are deadly zoonotic infections that have arisen into human populaces these previous 15 years. These Covids are related with novel respiratory disorder that spread from individual to-individual through close contact, bringing about high grimness and mortality brought about by the movement to Acute Respiratory Distress Syndrome (ARDS). Zones covered: The dangers of reappearance of SARS-CoV from bat repository has, the perseverance of MERS-CoV flow, and the potential for future development of novel Covids show antiviral medication disclosure will require movement against different Covids. In this survey, moves toward that alienate viral nonstructural proteins, kill underlying proteins, or balance basic host components of viral contamination with differing levels of viability in models of profoundly pathogenic Covid sickness are examined. Well-qualified assessment: Treatment of SARS and MERS in flare-up settings has zeroed in on therapeutics with general antiviral movement and great security profiles instead of adequacy information gave by cell, rat, or nonhuman primate models of exceptionally pathogenic Covid disease. In light of exercises gained from SARS and MERS flare-ups, absence of medications fit for container Covid antiviral action expands the weakness of general wellbeing frameworks to an exceptionally pathogenic Covid pandemic.

Drug discovery and Development

Drug Discovery may be a branch in pharmacy during which invention of potent drug entities is that the important role to be involved. The major part of drug design involves the identification of characteristic diagnostic biomarkers such as a protein responsible for the disease or disorder and then developing a drug molecule of therapeutic potency that targets it. The process involves various branches of pharmacology coalesce with biotechnology, bioinformatics, molecular biology, nanotechnology and biochemistry that ultimately leads to the production of molecules of therapeutic value. Despite the advancements in modern technologies and an understanding of the biological systems, the drug discovery process is still a lengthy and expensive task. There are only a few therapeutic drugs that pass the test and enter the market but today's accelerated studies using computational drug design techniques speed up the process of drug discovery.

• Diagnostic markers as therapeutic targets
• Approaches in target identification and validation
• In silico pharmacology
• Drug design and molecular modeling
• Molecular docking studies

Pharmaceutical Analysis and developments
Pharmaceutical Analysis is an Analytical Method wont to determination the standard and quantity of the pharmaceutical products. It also gives the knowledge about the purity and safety of the products. Briefly it are often described because it identifies, determines, quantifies, purifies and separates the active compound from the mixture.

Drug Delivery Technologies Pharmaceutical Delivery

Technologies are primarily centered around improving the medication retention, tolerant experience and adequacy of Drug. Bioavailability of prescriptions inside the framework is regularly accomplished by expanding the disintegration rate with particular medication conveyance upgrade items. By expanding the most recent Technologies for Drug-conveyance it is conceivable to build its business achievement. The fundamental courses of medication conveyance are oral, infusion/mixture, and transdermal. Medication eluting stents and other implantable medication conveyance gadgets are introduced, just as remotely applied gadgets. At the point when joined with fitting focusing on moieties, drug-covered nanoparticles, drug-epitomizing liposomes and nanotubes, and tree-like dendrimers empower organ and tissue focusing on.
In the new year’s we can see the fast spread of nanotechnology in the field of medication and seen in different parts of medication conveyance. In present situation different substances are under scrutiny for the treatment of medication conveyance and generally focused on malignancy treatment. What's more, as a new improvement, drug sciences use nanoparticles to diminish the symptoms of medications and even up to didn't understand the transporter framework that is force to chance to the patient.
The sort of dangers that are presented by utilizing nanoparticles for drug conveyance are past that presented by traditional perils forced by synthetics in old style conveyance networks

Pharmaceutical Drug Discovery and Nanotechnology

Nanotechnology has now introduced to develop medicine. Nanotechnology contains the utilization of materials with essential length scales within the nanometer measurement which demonstrate significantly changed properties associated to micron structured materials. Such materials can include particles, fibers, grain sizes, etc. This session highlighted the progression nanotechnology is making in medicine in such fields as disease prevention, diagnosis, and treatment including (but not limited to) drug delivery, tissue engineering, implants, sensors, cancer treatment an (but not limited to) drug delivery, transplants, tissue engineering, and toxic.

Medicinal Chemistry in Drug Discovery

The latest drug discovery system brings many advancements and developments within the new drugs. Now a days new organic targets, procedures and progressed figuring have improved current medication revelation and have given therapeutic science a more insightful range of abilities and toolbox to hold the subtleties of infection pathophysiology. The mixture of both medicinal chemistry and methodology in drug discovery together makes drug delivery more efficient and more lessening attrition. In medication planning, structure-based medication plan, and piece – based medication plan, regular item based medication plan, variety based medication plan, and chemo genomics are applied.
• Protein Kinases in Immunology and Oncology
• Inhibitors Discovery Strategies in Medicinal Chemistry
• Medicinal Chemistry for Autoimmune Diseases
• Neuroscience Drug Discovery
• CNS – Interfacing Chemistry and Biology to Advance

Nanotechnology & Drug Discovery

As we observe within the recent days, it's seen that nanotechnology has become the foremost significant interest to the wide selection of area in pharmaceutical industry. Nanomaterials are used in-vivo preclinical and clinical trials. The selection of a particular techniques or methods is based on administration routes, dose, drug target, drug physicochemical properties, target cells or tissues. All diverse nano sized structures has been investigated in order to get drug delivery and drug formulations. The nano-sized crystalline drug, drug-polymer and drug-antibody conjugates, dendrimers, liposomes, lipid emulsions, and solid drug-polymer nanoparticle dispersions are a number of the drug carriers containing nanomaterial.
• Therapeutic properties of nanomaterials
• Nanoparticles as drug vehicles
• Role of nanotechnology in drug design and manufacture
• Biocompatibility of nanoparticles
• Regenerative Therapeutics

Major Challenges in Drug Delivery and Discovery

As our focus is on major challenges of drug delivery in drug delivery technology industry. The sessions included during this are Reducing Patient Compliance, overcoming challenges in pediatric drug delivery, Drug Delivery of poorly soluble drugs, Polymeric enhancement because the drug delivery system, controlling the addictive nature of drugs. The demand for non-invasive drug delivery is increasing effectively, ideally and non-invasive drug delivery methods. The overwhelming growth in the case of biopharmaceutical sector is seen due to the advances in biotechnology. As we see in 2009, over $12 billion were invested in biologics and biotechnology research and development (R&D), which is contributing a 26% share in the total R&D expenditure. As the recent report takes that Pharmaceutical Research and makers of America (PhRMA) in 2015, there are nearly 901 biologicals in development, targeting quite 100 diseases.

Computer Applications in Pharmacy

Computers are now a days utilized in pharmaceutical industries, hospitals and in various sectors for the knowledge about Drug, education, evaluation, analysis, medication history and for maintenance of the monetary records. They have become indispensable within the event of clinical pharmacy, hospital pharmacy and pharmaceutical research. Computers are also useful for patient profile medication, monitoring, management and material management. It is useful in providing the drug information services, drug interactions and patient counselling.

Computer Aided Drug Design (CADD)

The process of planning a substitution drug by utilizing bioinformatics executes have opened a substitution territory of medication examination and development.Computational strategies help us in looking through different medication targets and in Drug-Formulation planning drug.
Drug Discovery 2021 and bioinformatics affects drug formulation and new drug design within the fallowing drug design path.
By using computational methods and the 3D structural information of the protein target, we are now able to scrutinize the detailed underlying molecular and atomic interactions involved in ligand: protein interactions and thus interpret experimental results in detail. The use of computers in drug formulation and drug discovery bears the extra advantage of delivering new drug candidates sooner and cost-efficiently. Computer-aided drug discovery has recently had important successes in drug formulation: new ligands are predicted along side their receptor-bound structures and in several circumstances the achieved hit rates (ligands discovered per molecules tested) are significantly greater than through experimental high-throughput screening.

Cancer Targeted Drug Delivery

Targeted drug delivery systems are the way to deliver the payload to the desired site of action without the interaction with normal cells. The number of targeted drug delivery systems like use of microfluidics, nanoparticle-based formulations and therefore the use of monoclonal antibodies for anticancer drugs are within the market and lots of more are in research phase. Successful translations of potential cancer, gene therapies and particularly small interfering RNA delivery (siRNA) will largely depends on targeted drug delivery strategies. In future, the advancements in these approaches can reach to significant improvements in cancer therapy procedures to avoid risks associate with chemotherapy in these methodologies.

Pharmaceutical Science

The pharmaceutical sciences combine a broad range of scientific disciplines that are critical to the invention and development of latest drugs and therapies. Pharmaceutical sciences are often broadly classified into the next main categories, with many specialized fields within each category.
Over the years, pharmaceutical scientists are instrumental in discovering and developing innovative drugs that save thousands of people’s lives and improve the standard of life for several others. Pharmaceutical scientists can pursue a spread of jobs. they're employed by pharmaceutical companies, they work as pharmacists, doctors, and as researchers and professors at universities, as regulatory scientists for agencies a bit like the Food and Drug Administration (FDA), and as researchers at national laboratories like the National Institutes of Health (NIH).

Cardiovascular Drug Delivery

Cardiovascular diseases are projected to affect populace across the planet. Cardiovascular diseases contain diseases and disorders associated with heart and blood vessels. Numerous drugs are accessible and are under development for treating cardiovascular diseases based on various signs such as arrhythmia, myocardial infarction, and atherosclerosis. The global range of cardiovascular drug has been involved into many sorts of medicine . Some of the most cardiovascular drugs include anti-hypertensive drugs like calcium channel blockers and angiotensin II receptor antagonists, and hypolipidemic drugs.

Drug Delivery and Design Development

In this session we'll specialise in Medical Devices designed for drug delivery through the pulmonary and nasal routes. These courses are of interest for neighborhood conveyance, as in asthma, yet additionally for quick conveyance of medications to the framework flow and direct conveyance to the focal sensory system . The particular anatomical and mental accounted intranasal and pneumonic courses may be included. Medication conveyance gadgets are the particular devices that are utilized for conveying of a medication through explicit course of organization. Such gadgets are utilized as a piece of at least one clinical medicines.As many of the industries felt that it's unnecessary to feel this health care as a posh problem then it delays in maintaining the higher health care. But as it is needful to change that perception, last year FDA announces around $40 million to a new Medical Device Innovation Consortium (MDIC) that is charged with simplifying the process of designing and testing the new technologies. With the input taken from industry, government and some non-profit organizations along with some public private MDIC will prioritize the regulatory science needs of the community and fund rising projects to streamline the process easily.
Current research on femtosecond laser micro fabrication of fluidic devices is introduced to present their research to elaborate. The research areas on microfluidics provide a good range of sensitive microfluidic sensors for practical applications with the added advantage of low-cost portability, efficiency, sensitivity and versatility.

Pharmacology and new innovations

Pharmacology is that the science of drugs and their effect on living systems. In medicine cabinets, once you visit the dentists and once you take any sort of medication. Pharmacology is additionally liable for painkillers, caffeine drinks and antibiotics. it's the science of what's happening to your body and to the drug itself.
Every medication we take alters the chemistry within our body. The role of pharmacology is to know why these changes are happening, allowing us to develop better drugs.
Pharmacological knowledge improves the lives of many people across the planet . It maximizes their benefit and minimizes risk and harm. As new diseases emerge, and older medicines - like antibiotics - not work also, the contribution of pharmacology to finding better and safer medicines becomes more vital.

Radiopharmaceutical

A Radiopharmaceutical may be a drug which will be used either for diagnostic or therapeutic purposes. It is a composition of radioisotope bond to an organic molecule. The organic molecule conveys the radioisotope to the specific organs and tissues or cells. The radioisotope is selected for its properties.

Radiopharmaceuticals are drugs that contains radioactive substances called radioisotopes. Radioisotopes are atoms that emits radiation as gamma rays or particles. In some cases, radiopharmaceuticals use radioisotopes that emit a mixture of those sorts of radiation.

The propelling factors for the expansion of the drug discovery market include the rising prevalence of a good range of diseases (such as cardiovascular and CNS-related disorders), rising healthcare expenditure, and upcoming patent expiration of blockbuster drugs. The diverse range of diseases, primarily disorder, infectious diseases, diabetes, and kidney-related complications, features a high prevalence, globally. Thus, the increasing prevalence of a various range of diseases among all age groups and its burden, globally, drives the demand for drug discovery and its market. There has been an upsurge within the usage of advanced technologies, like high throughput, bioinformatics and combinatorial chemistry for better drug candidate identification. Drug discovery has evolved significantly with emerging technologies, helping the method to become more refined, accurate, and fewer time consuming. Due to automation, multi-detector readers, imaging hardware and software, high-throughput screening is one among the foremost widely used drug discovery technologies. In recent years, there has been a rising demand for speciality medicines that are expected to ultimately influence the tiny molecule drug discovery market during a positive manner, as most of the speciality medicines are small molecules. The gradual rise within the healthcare expenditure regionally helps the new pharmaceutical technology advancement. Although with high expenditure, there's a requirement for redirecting the resources, the transition toward better usability of healthcare expenditure for drug development is under progress.

Scope of the Report

As per the scope of the report, drug discovery may be a process, which aims at identifying a compound therapeutically useful in treating and curing diseases. Typically, a drug discovery effort addresses a biological target that has been shown to play a task within the development of the disease or starts from a molecule with interesting biological activities. In the recent past, drug discovery has evolved significantly with emerging technologies, helping the method to become more refined, accurate, and fewer time consuming.

The feat of 3rd World Conference on Pharmaceutical Research and Drug Discovery well thought-out by Conference Series Ltd that was apprehended during December 03-04, 2020 was a prodigious standard. Massive number of partakers from round the ecosphere had spoken on diverse sessions.

We gratefully thank all our wonderful Speakers, Conference Attendees, Students, Media Partners, and Associations for making Drug Discovery 2020 Conference the best ever! The Meeting enduring with Keynote dialogs by the renowned speakers Dr. Magnus S Magnusson, Iceland, Mr. Jams Otniel Rychard Rumahorbo, Indonesia from the fabled establishments and verbal talks from the finest and top hierarchical doctor of medicine from varied departments who are consistent to this arena. Investigation Specialists, students and demonstrations are the special fascinations which made the experience alive through their doubts and explores.

Presenters of this event as below:
Day 1: Networking & Refreshment
Day 2: Morning Session

Talk 1: Unique mass-social lifestyle change: T-pattern based self-similarity between nano to human scales in a biological eyeblink by Magnus S Magnusson, Iceland
Tracks: Drug discovery and Development| Drug Delivery Technologies| Pharmaceutical Drug Discovery and Nanotechnology| Medicinal Chemistry in Drug Discovery| Nanotechnology & Drug Discovery| Major Challenges in Drug Delivery and Discovery

Talk 2: Newest traditional medicinal formulation “Methuselah V-day 969”shocked the world in the 20th century by Jams Otniel Rychard Rumahorbo, Indonesia
Talk 3: Application of virtual reality in medical training: Is it worth it? By Andrea Luca, Italy
Talk 4: High resolution melting typing (HRMT) is suitable for real time hospital surveillance by Matteo Perini, Italy and many more.

Conference Series Ltd gives proper gratitude to Organizing Committee Members nimble of field various external professionals business enterprise councils and is obliged to different renowned personalities who interlocked with us and bolstered the symposium in each facet without which the convention might now not were possible. And bolstered the symposium in each facet without which the convention might now not were possible. Your reaction is our inspiration; preserving this motto in thoughts and being discovered the triumph of Drug Discovery 2020

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Conference Date	December 16-17, 2021
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7^th World Congress on Pharmaceutical Research & Drug Discovery December 16-17, 2021 Barcelona, Spain

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